Title : Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease.

Pub. Date : 2006 Nov 6

PMID : 16959224






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Memantine increased Bcl-xl and decreased Bax level. Memantine Bcl2-like 1 Rattus norvegicus
2 Memantine increased Bcl-xl and decreased Bax level. Memantine BCL2 associated X, apoptosis regulator Rattus norvegicus
3 Memantine also exerted an inhibitory effect on the micro-calpain level and decreased the huntingtin proteolytic fragments. Memantine huntingtin Rattus norvegicus