| 51 | 21490315 | Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER. | Am J Physiol Cell Physiol | 2011 Jul |
3 |
| 52 | 21919210 | Understanding of molecular substructures that contribute to hERG K+ channel blockade: synthesis and biological evaluation of E-4031 analogues. | ChemMedChem | 2012 Jan 2 |
1 |
| 53 | 22028871 | Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology. | PLoS One | 2011 |
1 |
| 54 | 22075718 | Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells. | Pflugers Arch | 2012 Feb |
2 |
| 55 | 22161019 | Imatinib has the potential to exert its antileukemia effects by down-regulating hERG1 K+ channels in chronic myelogenous leukemia. | Med Oncol | 2012 Sep |
1 |
| 56 | 22198052 | A novel method of selecting human embryonic stem cell-derived cardiomyocyte clusters for assessment of potential to influence QT interval. | Toxicol In Vitro | 2012 Mar |
1 |
| 57 | 22292854 | Human ether-a-go-go-related gene K+ channels regulate shedding of leukemia cell-derived microvesicles. | Leuk Lymphoma | 2012 Aug |
1 |
| 58 | 22498908 | Development of recombinant cell line co-expressing mutated Nav1.5, Kir2.1, and hERG for the safety assay of drug candidates. | J Biomol Screen | 2012 Jul |
1 |
| 59 | 22889737 | Sphingosine 1-phosphate and human ether-a'-go-go-related gene potassium channels modulate migration in human anaplastic thyroid cancer cells. | Endocr Relat Cancer | 2012 Oct |
1 |
| 60 | 22936309 | hERG ion channel pharmacology: cell membrane liposomes in porous-supported lipid bilayers compared with whole-cell patch-clamping. | Eur Biophys J | 2012 Nov |
1 |
| 61 | 23020479 | Chaotic dynamics in cardiac aggregates induced by potassium channel block. | Chaos | 2012 Sep |
1 |
| 62 | 23050739 | Differential effects of blockade of ERG channels on gamma oscillations and excitability in rat hippocampal slices. | Eur J Neurosci | 2012 Dec |
1 |
| 63 | 23138560 | Functional expression of ERG1 potassium channels in rat alveolar macrophages. | J Mol Histol | 2013 Feb |
4 |
| 64 | 23160842 | hERG drug response measured in droplet bilayers. | Biomed Microdevices | 2013 Apr |
1 |
| 65 | 25219538 | Human stem cell-derived cardiomyocytes detect drug-mediated changes in action potentials and ion currents. | J Pharmacol Toxicol Methods | 2014 Nov-Dec |
1 |
| 66 | 25223792 | Conjoint propagation and differentiation of human embryonic stem cells to cardiomyocytes in a defined microcarrier spinner culture. | Stem Cell Res Ther | 2014 Sep 15 |
1 |
| 67 | 25546810 | Inhibition of IKr potentiates development of atrial-selective INa block leading to effective suppression of atrial fibrillation. | Heart Rhythm | 2015 Apr |
1 |
| 68 | 26617732 | Cardiac sodium/calcium exchanger preconditioning promotes anti-arrhythmic and cardioprotective effects through mitochondrial calcium-activated potassium channel. | Int J Clin Exp Pathol | 2015 |
1 |
| 69 | 26637557 | Contribution of the late sodium current to intracellular sodium and calcium overload in rabbit ventricular myocytes treated by anemone toxin. | Am J Physiol Heart Circ Physiol | 2016 Feb 1 |
1 |
| 70 | 27199074 | Pharmacological rescue of hERG currents carried out by G604S and wide type hERG co-expression. | Clin Exp Pharmacol Physiol | 2016 Sep |
6 |
| 71 | 27282640 | Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment. | J Pharmacol Toxicol Methods | 2016 Sep-Oct |
1 |
| 72 | 27704082 | Evaluation of drug-mediated arrhythmic changes in spontaneous beating cardiomyocytes by AFM. | Analyst | 2016 Nov 21 |
1 |
| 73 | 28448053 | Automated Contraction Analysis of Human Engineered Heart Tissue for Cardiac Drug Safety Screening. | J Vis Exp | 2017 Apr 15 |
1 |
| 74 | 28615142 | Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs. | J Pharmacol Sci | 2017 Jun |
2 |
| 75 | 28632743 | In silico assessment of the effects of quinidine, disopyramide and E-4031 on short QT syndrome variant 1 in the human ventricles. | PLoS One | 2017 |
1 |
| 76 | 29146210 | Novel intracellular transport-refractory mutations in KCNH2 identified in patients with symptomatic long QT syndrome. | J Cardiol | 2018 Apr |
1 |
| 77 | 29175952 | Modulation of Ether-à-Go-Go Related Gene (ERG) Current Governs Intrinsic Persistent Activity in Rodent Neocortical Pyramidal Cells. | J Neurosci | 2018 Jan 10 |
1 |
| 78 | 29555184 | Proarrhythmia risk prediction using human induced pluripotent stem cell-derived cardiomyocytes. | J Pharmacol Sci | 2018 Apr |
1 |
| 79 | 30800649 | Aggregation-Induced Emission: Lighting Up hERG Potassium Channel. | Front Chem | 2019 |
1 |
| 80 | 30807184 | Intracellular Mechanism of Rosuvastatin-Induced Decrease in Mature hERG Protein Expression on Membrane. | Mol Pharm | 2019 Apr 1 |
1 |
| 81 | 31017964 | Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells. | PLoS One | 2019 |
2 |
| 82 | 31520926 | Discovery of a potent p38α/MAPK14 kinase inhibitor: Synthesis, in vitro/in vivo biological evaluation, and docking studies. | Eur J Med Chem | 2019 Dec 1 |
1 |
| 83 | 32321643 | Serine mutation of a conserved threonine in the hERG K<sup>+</sup> channel S6-pore region leads to loss-of-function through trafficking impairment. | Biochem Biophys Res Commun | 2020 Jun 11 |
1 |
| 84 | 32390841 | hERG K<sup>+</sup> Channels Promote Survival of Irradiated Leukemia Cells. | Front Pharmacol | 2020 |
3 |
| 85 | 32587517 | K<sub>V</sub>11.1 Potassium Channel and the Na<sup>+</sup>/H<sup>+</sup> Antiporter NHE1 Modulate Adhesion-Dependent Intracellular pH in Colorectal Cancer Cells. | Front Pharmacol | 2020 |
2 |
| 86 | 33707655 | Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types. | Sci Rep | 2021 Mar 11 |
1 |
| 87 | 33986332 | A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues. | Sci Rep | 2021 May 13 |
1 |
| 88 | 34383081 | Inactivation of Native K Channels. | J Membr Biol | 2022 Feb |
1 |
| 89 | 34572598 | The Effect of a Synthetic Estrogen, Ethinylestradiol, on the hERG Block by E-4031. | Biomolecules | 2021 Sep 20 |
6 |
| 90 | 34681161 | Induced Pluripotent Stem Cell-Derived Cardiomyocytes with <i>SCN5A</i> R1623Q Mutation Associated with Severe Long QT Syndrome in Fetuses and Neonates Recapitulates Pathophysiological Phenotypes. | Biology (Basel) | 2021 Oct 18 |
1 |