Title : Pharmacological rescue of hERG currents carried out by G604S and wide type hERG co-expression.

Pub. Date : 2016 Sep

PMID : 27199074






6 Functional Relationships(s)
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1 In addition, E-4031 treatment shifted the steady-state half maximal activation voltage (V1/2 ) of the inactivation curve by +8 mV in cells co-expressing G604S-hERG and WT-hERG. E 4031 ETS transcription factor ERG Homo sapiens
2 In addition, E-4031 treatment shifted the steady-state half maximal activation voltage (V1/2 ) of the inactivation curve by +8 mV in cells co-expressing G604S-hERG and WT-hERG. E 4031 ETS transcription factor ERG Homo sapiens
3 E-4031 treatment resulted in a significant increase in hERG currents by promoting the hERG channel processing and trafficking in cells co-expressing G604S-hERG and WT-hERG. E 4031 ETS transcription factor ERG Homo sapiens
4 E-4031 treatment resulted in a significant increase in hERG currents by promoting the hERG channel processing and trafficking in cells co-expressing G604S-hERG and WT-hERG. E 4031 ETS transcription factor ERG Homo sapiens
5 E-4031 treatment resulted in a significant increase in hERG currents by promoting the hERG channel processing and trafficking in cells co-expressing G604S-hERG and WT-hERG. E 4031 ETS transcription factor ERG Homo sapiens
6 E-4031 treatment resulted in a significant increase in hERG currents by promoting the hERG channel processing and trafficking in cells co-expressing G604S-hERG and WT-hERG. E 4031 ETS transcription factor ERG Homo sapiens