Title : Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment.

Pub. Date : 2016 Sep-Oct

PMID : 27282640






1 Functional Relationships(s)
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1 RESULTS: Our data demonstrate that hERG channel blockers, such as E4031 and moxifloxacin, prolonged field potential duration (FPD) at low concentration and induced arrhythmic beating activity as measured by field potential (FP) recording and impedance (IMP) recordings at higher concentrations. E 4031 ETS transcription factor ERG Homo sapiens