Title : Evaluation of drug-mediated arrhythmic changes in spontaneous beating cardiomyocytes by AFM.

Pub. Date : 2016 Nov 21

PMID : 27704082






1 Functional Relationships(s)
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1 Preliminary results indicate that the hERG blocker E-4031 can stimulate irregular, arrhythmic beating patterns in the cardiomyocytes from both species, and that immediate subsequent treatment with the hERG enhancer nicorandil can rescue these back to regular beating patterns, similar to those observed when the cells were untreated. E 4031 ETS transcription factor ERG Homo sapiens