Title : New biaryl-chalcone derivatives of pregnenolone via Suzuki-Miyaura cross-coupling reaction. Synthesis, CYP17 hydroxylase inhibition activity, QSAR, and molecular docking study.

Pub. Date : 2015 Sep

PMID : 26051784






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A new class of steroids is being synthesized for its ability to prevent intratumoral androgen production by inhibiting the activity of CYP17 hydroxylase enzyme. Steroids cytochrome P450 family 17 subfamily A member 1 Homo sapiens