Title : Comparisons of Prostate Cancer Inhibitors Abiraterone and TOK-001 Binding with CYP17A1 through Molecular Dynamics.

Pub. Date : 2015

PMID : 26682016






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Cytochrome P450 17A1 (CYP17A1) is associated in the steroid hormone biosynthesis in human. Steroids cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Cytochrome P450 17A1 (CYP17A1) is associated in the steroid hormone biosynthesis in human. Steroids cytochrome P450 family 17 subfamily A member 1 Homo sapiens
3 As cell proliferation of prostate cancer in response to androgen steroid, an inhibition of CYP17A1 becomes an alternative approach to inhibit biosynthesis of androgen and support treatment of prostate cancer. Steroids cytochrome P450 family 17 subfamily A member 1 Homo sapiens