113 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
101 | 21807635 | Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants. | 2011 Sep 15 | 2 |
102 | 21868758 | Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. | 2011 Oct 15 | 4 |
103 | 20159824 | Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. | 2010 Mar 20 | 1 |
104 | 20399458 | A phase I clinical study of high dose ketoconazole plus weekly docetaxel for metastatic castration resistant prostate cancer. | 2010 Jun | 1 |
105 | 20550118 | Isopropylidene substitution increases activity and selectivity of biphenylmethylene 4-pyridine type CYP17 inhibitors. | 2010 Jul 8 | 1 |
106 | 20595043 | Molecular modeling on inhibitor complexes and active-site dynamics of cytochrome P450 C17, a target for prostate cancer therapy. | 2010 Jul 30 | 1 |
107 | 20684610 | Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prostate cancer. | 2010 Aug 12 | 1 |
108 | 19111799 | The Coffey Lecture: steroidogenic enzyme inhibitors and hormone dependent cancer. | 2009 Jan-Feb | 1 |
109 | 19211174 | Novel CYP17 inhibitors: synthesis, biological evaluation, structure-activity relationships and modelling of methoxy- and hydroxy-substituted methyleneimidazolyl biphenyls. | 2009 Jul | 1 |
110 | 19223900 | CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer. | 2009 Mar 10 | 1 |
111 | 19733987 | Beyond castration and chemotherapy: novel approaches to targeting androgen-driven pathways. | 2009 Oct 20 | 1 |
112 | 18672868 | Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer. | 2008 Aug 28 | 2 |
113 | 18985049 | CYP17 inhibition as a hormonal strategy for prostate cancer. | 2008 Nov | 1 |