Title : Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer.

Pub. Date : 2008 Aug 28

PMID : 18672868






2 Functional Relationships(s)
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1 Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer. abiraterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Abiraterone, a steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. abiraterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens