Cyclic AMP

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cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







37 Article(s)
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1 23415678 The relevance of chemical interactions with CYP17 enzyme activity: assessment using a novel in vitro assay. 2013 May 1 1
2 20160131 Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a. 2010 Apr 1
3 20534731 Impact of differential P450c17 phosphorylation by cAMP stimulation and by starvation conditions on enzyme activities and androgen production in NCI-H295R cells. 2010 Aug 7
4 20615422 Effects of fluorotelomer alcohol 8:2 FTOH on steroidogenesis in H295R cells: targeting the cAMP signalling cascade. 2010 Sep 15 1
5 19359379 Liver receptor homolog-1 regulates the transcription of steroidogenic enzymes and induces the differentiation of mesenchymal stem cells into steroidogenic cells. 2009 Aug 2
6 17786540 SMAD3 inhibits SF-1-dependent activation of the CYP17 promoter in H295R cells. 2008 Jan 1
7 17121866 Coregulator exchange and sphingosine-sensitive cooperativity of steroidogenic factor-1, general control nonderepressed 5, p54, and p160 coactivators regulate cyclic adenosine 3',5'-monophosphate-dependent cytochrome P450c17 transcription rate. 2007 Feb 1
8 17664281 Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17. 2007 Oct 5
9 16306078 Cyclic adenosine 5'-monophosphate-dependent sphingosine-1-phosphate biosynthesis induces human CYP17 gene transcription by activating cleavage of sterol regulatory element binding protein 1. 2006 Mar 1
10 16887917 Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1. 2006 Nov 2
11 16981135 Adenovirus-delivered DKK3/WNT4 and steroidogenesis in primary cultures of adrenocortical cells. 2006 Sep 1
12 14988427 GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1. 2004 May 1
13 15072559 The transcriptional regulating protein of 132 kDa (TReP-132) differentially influences steroidogenic pathways in human adrenal NCI-H295 cells. 2004 Apr 2
14 12506119 CAMP-dependent protein kinase enhances CYP17 transcription via MKP-1 activation in H295R human adrenocortical cells. 2003 Mar 7 4
15 12782406 Characterization of receptor-interacting protein RIP140 in the regulation of SF-1 responsive target genes. 2003 May 30 1
16 11897684 Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription. 2002 Apr 4
17 11956159 Adrenocorticotropin/cyclic adenosine 3',5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity. 2002 May 5
18 12200237 cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase A. 2002 Aug 2
19 12530662 Transcriptional complexes at the CYP17 CRS. 2002 Nov 5
20 11463853 NF-1C, Sp1, and Sp3 are essential for transcription of the human gene for P450c17 (steroid 17alpha-hydroxylase/17,20 lyase) in human adrenal NCI-H295A cells. 2001 Aug 1
21 10720067 17alpha-hydroxylase/17,20-lyase deficiency as a model to study enzymatic activity regulation: role of phosphorylation. 2000 Mar 1
22 10852468 Differential activity of the cytochrome P450 17alpha-hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells. 2000 Jun 1
23 10919257 Interactive stimulation by luteinizing hormone and insulin of the steroidogenic acute regulatory (StAR) protein and 17alpha-hydroxylase/17,20-lyase (CYP17) genes in porcine theca cells. 2000 Aug 1
24 11196414 Orphan receptors COUP-TF and DAX-1 as targets in disordered CYP17 expression in adrenocortical tumors. 2000 Nov 1
25 11196462 Expression and regulation of BCL-2 family genes in human adrenocortical adenomas in comparison with adrenal hyperplasia of Cushing's disease. 2000 Nov 1
26 9851803 COUP-TFI expression in human adrenocortical adenomas: possible role in steroidogenesis. 1998 Dec 1
27 9024219 Transcription of the human genes for cytochrome P450scc and P450c17 is regulated differently in human adrenal NCI-H295 cells than in mouse adrenal Y1 cells. 1997 Feb 2
28 9029728 The regulation of 17,20 lyase activity. 1997 Jan 1
29 9390195 The homeodomain protein Pbx1 is involved in cAMP-dependent transcription of human CYP17. 1997 Dec 1 2
30 7479852 Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome. 1995 Nov 7 1
31 8597483 Adrenal androgen biosynthesis with special attention to P450c17. 1995 Dec 29 1
32 7811386 Molecular cloning and expression of guinea pig cytochrome P450c17 cDNA (steroid 17 alpha-hydroxylase/17,20 lyase): tissue distribution, regulation, and substrate specificity of the expressed enzyme. 1994 Dec 1
33 1311271 Distinct biochemical mechanisms for cAMP-dependent transcription of CYP17 and CYP21. 1992 Jan 6 1
34 22217838 Comparison of cAMP-responsive DNA sequences and their binding proteins associated with expression of the bovine CYP17 and CYP11A and human CYP21B genes. 1992 Dec 2
35 1964490 Tissue-specific, cyclic adenosine 3',5'-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells. 1990 Dec 1
36 3349907 Developmental and hormonal regulation of mRNAs for insulin-like growth factor II and steroidogenic enzymes in human fetal adrenals and gonads. 1988 Jan-Feb 1
37 3034954 Hormonal regulation of messenger ribonucleic acids for P450scc (cholesterol side-chain cleavage enzyme) and P450c17 (17 alpha-hydroxylase/17,20-lyase) in cultured human fetal adrenal cells. 1987 Jul 1