Pub. Date : 1997 Dec 1
PMID : 9390195
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The homeodomain protein Pbx1 is involved in cAMP-dependent transcription of human CYP17. | Cyclic AMP | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | 5"-Deletion analyses of the reporter construct containing this Pbx-binding site showed approximately sixfold induction by coexpression of Pbx1 and PKA compared to the basal transcription, suggesting that Pbx1 binds the -250/-241 bp sequence and participates in cAMP-dependent regulation of the human CYP17 gene. | Cyclic AMP | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |