Title : Effects of fluorotelomer alcohol 8:2 FTOH on steroidogenesis in H295R cells: targeting the cAMP signalling cascade.

Pub. Date : 2010 Sep 15

PMID : 20615422






1 Functional Relationships(s)
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1 Exposure to 8:2 FTOH significantly down-regulated cAMP-dependent mRNA expression and protein abundance of several key steroidogenic enzymes, including StAR, CYP11A, CYP11B1, CYP11B2, CYP17 and CYP21. Cyclic AMP cytochrome P450 family 17 subfamily A member 1 Homo sapiens