Morphine

glutamate ionotropic receptor NMDA type subunit 1 ; Rattus norvegicus







34 Article(s)
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1 33516802 Donepezil attenuates the development of morphine tolerance in rats with cancer-induced bone pain: The role of cortical N-methyl-D-aspartate receptors. 2021 Mar 16 2
2 33774150 Hydrogen enriched saline alleviates morphine tolerance via inhibiting neuroinflammation, GLT-1, GS nitration and NMDA receptor trafficking and functioning in the spinal cord of rats. 2021 Jun 11 1
3 34058253 Donepezil prevents morphine tolerance by regulating N-methyl-d-aspartate receptor, protein kinase C and CaM-dependent kinase II expression in rats. 2021 Jul 3
4 31760085 Blockade of peripheral nociceptive signal input relieves the formation of spinal central sensitization and retains morphine efficacy in a neuropathic pain rat model. 2020 Jan 18 1
5 32335205 The effect of microinjection of CART 55-102 into the nucleus accumbens shell on morphine-induced conditioned place preference in rats: Involvement of the NMDA receptor. 2020 Jul 1
6 31220544 Spinal Serum- and Glucocorticoid-Regulated Kinase 1 (SGK1) Signaling Contributes to Morphine-Induced Analgesic Tolerance in Rats. 2019 Aug 10 1
7 28423675 miR-219-5p targets CaMKIIγ to attenuate morphine tolerance in rats. 2017 Apr 25 1
8 27563417 Morphine-Induced Analgesic Tolerance Effect on Gene Expression of the NMDA Receptor Subunit 1 in Rat Striatum and Prefrontal Cortex. 2016 Jul 3
9 27803778 Association of morphine-induced analgesic tolerance with changes in gene expression of GluN1 and MOR1 in rat spinal cord and midbrain. 2016 Sep 4
10 25745356 Melatonin prevents morphine-induced hyperalgesia and tolerance in rats: role of protein kinase C and N-methyl-D-aspartate receptors. 2015 3
11 24713351 Midazolam exacerbates morphine tolerance and morphine-induced hyperactive behaviors in young rats with burn injury. 2014 May 20 2
12 24841769 Spinal leptin contributes to the development of morphine antinociceptive tolerance by activating the STAT3-NMDA receptor pathway in rats. 2014 Aug 1
13 22309983 Amitriptyline attenuates astrocyte activation and morphine tolerance in rats: role of the PSD-95/NR1/nNOS/PKCγ signaling pathway. 2012 Apr 15 3
14 22531378 Morphine and MK-801 administration leads to alternative N-methyl-D-aspartate receptor 1 splicing and associated changes in reward seeking behavior and nociception on an operant orofacial assay. 2012 Jul 12 1
15 22713680 Resveratrol regulates N-methyl-D-aspartate receptor expression and suppresses neuroinflammation in morphine-tolerant rats. 2012 Oct 2
16 20950603 Agmatine modulates neuroadaptations of glutamate transmission in the nucleus accumbens of repeated morphine-treated rats. 2011 Jan 10 2
17 21861871 Dextromethorphan attenuated the higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat offspring. 2011 Aug 23 3
18 20478329 Co-administration of ultra-low dose naloxone attenuates morphine tolerance in rats via attenuation of NMDA receptor neurotransmission and suppression of neuroinflammation in the spinal cords. 2010 Aug 2
19 20938337 Purinergic P2X receptor regulates N-methyl-D-aspartate receptor expression and synaptic excitatory amino acid concentration in morphine-tolerant rats. 2010 Nov 5
20 19041927 Prenatal morphine alters the synaptic complex of postsynaptic density 95 with N-methyl-D-aspartate receptor subunit in hippocampal CA1 subregion of rat offspring leading to long-term cognitive deficits. 2009 Feb 18 1
21 19348736 Inhibitory effects of Group I metabotropic glutamate receptors antagonists on the expression of NMDA receptor NR1 subunit in morphine tolerant rats. 2009 Mar 20 5
22 18391508 Morphine-induced behavioral sensitization increased the mRNA expression of NMDA receptor subunits in the rat amygdala. 2008 1
23 17321516 Nucleus accumbens NMDA receptor subunit expression and function is enhanced in morphine-dependent rats. 2007 May 21 2
24 16453311 Chronic morphine treatment alters expression of N-methyl-D-aspartate receptor subunits in the extended amygdala. 2006 Mar 2
25 16964763 Attenuation of morphine tolerance and withdrawal syndrome by coadministration of nalbuphine. 2006 Aug 1
26 15388787 An antisense oligonucleotide to the N-methyl-D-aspartate (NMDA) subunit NMDAR1 attenuates NMDA-induced nociception, hyperalgesia, and morphine tolerance. 2005 Feb 3
27 16319314 Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor. 2005 Nov 30 8
28 15266550 Decreased plasma membrane targeting of NMDA-NR1 receptor subunit in dendrites of medial nucleus tractus solitarius neurons in rats self-administering morphine. 2004 Sep 15 5
29 15287884 Dopamine and cyclic AMP-regulated phosphoprotein-32 phosphorylation pattern in cocaine and morphine-sensitized rats. 2004 Aug 1
30 12829326 Region-specific changes in NMDA receptor mRNA induced by chronic morphine treatment are prevented by the co-administration of the competitive NMDA receptor antagonist LY274614. 2003 Jun 10 5
31 14636974 The effect of drugs of abuse on NMDAR1 receptor expression in the rat limbic system. 2003 Nov 24 3
32 11858765 Single dose of morphine influences plasma corticosterone and gene expression of main NMDA receptor subunit in the adrenal gland but not in the hippocampus. 2001 Dec 1
33 9543234 Acute effects of morphine on the expression of mRNAs for NMDA receptor subunits in the rat hippocampus, hypothalamus and spinal cord. 1998 Jan 12 1
34 9716349 NMDA-R1 antisense oligonucleotide attenuates withdrawal signs from morphine. 1998 Jul 10 1