Pub. Date : 2003 Nov 24
PMID : 14636974
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acute or chronic morphine and cocaine administration increased NMDAR1 mRNA level in the central and basolateral nuclei of the amygdala; morphine did so 3 h after the last dose and 48 h after withdrawal, cocaine 3 h after acute and last chronic dose. | Morphine | glutamate ionotropic receptor NMDA type subunit 1 | Rattus norvegicus |
| 2 | Our study suggests a possible link between the expression of NMDAR1 and changes in limbic system neuronal activity and behaviour after administration of morphine and cocaine. | Morphine | glutamate ionotropic receptor NMDA type subunit 1 | Rattus norvegicus |
| 3 | In summary, the present study demonstrated that morphine and cocaine influenced the expression of NMDAR1 in the structure of the limbic system which could be involved in dependence phenomena. | Morphine | glutamate ionotropic receptor NMDA type subunit 1 | Rattus norvegicus |