Tyrosine

tumor necrosis factor ; Homo sapiens







163 Article(s)
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1 34536415 Early-onset pulmonary and cutaneous vasculitis driven by constitutively active SRC-family kinase HCK. 2022 Apr 1
2 33133025 Intrinsic Restriction of TNF-Mediated Inflammatory Osteoclastogenesis and Bone Resorption. 2020 1
3 28921811 A role for the non-receptor tyrosine kinase ACK1 in TNF-alpha-mediated apoptosis and proliferation in human intestinal epithelial caco-2 cells. 2018 Sep 1
4 29796172 Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies. 2018 May 1 1
5 30381640 [Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction]. 2018 1
6 27626315 Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy. 2016 Nov 15 1
7 25586176 Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes. 2015 Feb 27 1
8 26017975 Pleiotropic signaling evoked by tumor necrosis factor in podocytes. 2015 Jul 15 1
9 23319318 Mycophenolic acid regulates spleen tyrosine kinase to repress tumour necrosis factor-alpha-induced monocyte chemotatic protein-1 production in cultured human aortic endothelial cells. 2013 Jan 1
10 23995107 Characterisation of apoptosis in myb-transformed hematopoietic cell (MTHC-A) lines: TNF-α-induced apoptosis and prevention by cAMP. 2013 1
11 25006397 Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension. 2013 Dec 1
12 22365144 Perturbations of the actin cytoskeleton activate a Dictyostelium STAT signalling pathway. 2012 May 1
13 22530913 Generation of pharmacophore and atom based 3D-QSAR model of novel isoquinolin-1-one and quinazolin-4-one-type inhibitors of TNFα. 2012 May 2
14 22609131 From excess adiposity to insulin resistance: the role of free fatty acids. 2012 Sep-Oct 1
15 22937039 Fc gamma receptor CD64 modulates the inhibitory activity of infliximab. 2012 1
16 22988345 The EGF receptor and HER2 participate in TNF-α-dependent MAPK activation and IL-8 secretion in intestinal epithelial cells. 2012 1
17 23131831 Novel Phosphorylations of IKKγ/NEMO. 2012 Nov 6 4
18 23221158 Tumor necrosis factor α stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells. 2012 1
19 21168390 Insulin receptor substrates form high-molecular-mass complexes that modulate their availability to insulin/insulin-like growth factor-I receptor tyrosine kinases. 2011 Jan 21 1
20 21813649 Cyclin-dependent kinase-5 is a key molecule in tumor necrosis factor-α-induced insulin resistance. 2011 Sep 23 1
21 22110065 Role of β-adrenergic receptor regulation of TNF-α and insulin signaling in retinal Muller cells. 2011 Dec 16 1
22 19782747 TNFalpha activation of PKCdelta, mediated by NFkappaB and ER stress, cross-talks with the insulin signaling cascade. 2010 Feb 1
23 20006573 Tumor Necrosis Factor alpha (TNFalpha) regulates CD40 expression through SMAR1 phosphorylation. 2010 Jan 8 1
24 20208423 S-Adenosyl-L-methionine ameliorates TNFalpha-induced insulin resistance in 3T3-L1 adipocytes. 2010 May 31 1
25 20393185 Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymphoma. 2010 Jul 1
26 20644716 Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production. 2010 Jul 13 1
27 19426869 Isolation of regulatory-competent, phosphorylated cytochrome C oxidase. 2009 1
28 18080320 Two modes of ERK activation by TNF in keratinocytes: different cellular outcomes and bi-directional modulation by vitamin D. 2008 May 15 1
29 18325328 Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs. 2008 May 9 1
30 18372392 Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling. 2008 May 2
31 18420487 Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators. 2008 Jul 1
32 18465784 Expression and tyrosine phosphorylation of Crk-associated substrate lymphocyte type (Cas-L) protein in human neutrophils. 2008 Sep 1 2
33 18678606 Regulation of STAT pathways and IRF1 during human dendritic cell maturation by TNF-alpha and PGE2. 2008 Nov 1
34 16960890 Long-term effects of tumor necrosis factor-alpha treatment on insulin signaling pathway in HepG2 cells and HepG2 cells overexpressing constitutively active Akt/PKB. 2007 Feb 15 1
35 16985255 Degradation of STAT5 proteins in 3T3-L1 adipocytes is induced by TNF-{alpha} and cycloheximide in a manner independent of STAT5A activation. 2007 Feb 1
36 17184177 Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its complications. 2007 Mar 1
37 17251321 Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1. 2007 May 2
38 17481767 Impact of mitochondrial ROS production in the pathogenesis of insulin resistance. 2007 Sep 2
39 17637199 Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-alpha. 2007 Jul 2
40 17664271 Tumor necrosis factor receptor-1 can function through a G alpha q/11-beta-arrestin-1 signaling complex. 2007 Sep 28 2
41 17766589 Tumor necrosis factor-alpha causes barrier dysfunction mediated by tyrosine198 and tyrosine218 in beta-actin. 2007 Nov 4
42 17940969 Breakdown of paraendothelial barrier function during Marburg virus infection is associated with early tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1. 2007 Nov 15 3
43 16275893 Chemical inhibitors of TNF signal transduction in human neutrophils point to distinct steps in cell activation. 2006 Jan 2
44 16427093 Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor-alpha-induced IL-8 secretion in the human airway epithelial cell line NCI-H292. 2006 May 22 1
45 16644673 Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling. 2006 May 1
46 16891393 TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia. 2006 Dec 3
47 15721320 Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain. 2005 Apr 1 4
48 15927448 Signaling to the DEAD box--regulation of DEAD-box p68 RNA helicase by protein phosphorylations. 2005 Dec 2
49 16048438 STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells. 2005 Dec 1 1
50 16186396 Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. 2005 Oct 1