Title : Characterisation of apoptosis in myb-transformed hematopoietic cell (MTHC-A) lines: TNF-α-induced apoptosis and prevention by cAMP.

Pub. Date : 2013

PMID : 23995107






1 Functional Relationships(s)
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1 The apoptotic effect of TNF-alpha in MTHC-A was mimicked by a specific inhibitor of protein kinase A (PKI 5-24) and by the tyrosine kinase inhibitor genistein, suggesting that phosphorylation of tyrosine and PKA activity were important in protecting MTHC from apoptosis. Tyrosine tumor necrosis factor Homo sapiens