Pub. Date : 2006 May
PMID : 16644673
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | TNF-alpha significantly activated ASK1, increased serine phosphorylation of insulin receptor substrate (IRS)-1, and decreased insulin-stimulated tyrosine phosphorylation of IRS-1 and serine phosphorylation of Akt, and all of these effects were inhibited by overexpression of either UCP-1 or MnSOD. | Tyrosine | tumor necrosis factor | Homo sapiens |