Tyrosine

T cell receptor beta variable 20/OR9-2 (non-functional) ; Homo sapiens







222 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35186948 TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity. 2021 1
2 31674657 Actin polymerization regulates recruitment of Nck to CD3ε upon T-cell receptor triggering. 2020 Mar 1
3 30018141 GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion. 2018 Sep 7 2
4 28465009 Crk adaptor proteins regulate CD3ζ chain phosphorylation and TCR/CD3 down-modulation in activated T cells. 2017 Aug 1
5 28515365 Ceramide synthesis regulates T cell activity and GVHD development. 2017 May 18 1
6 28526413 TCR crosslinking promotes Crk adaptor protein binding to tyrosine-phosphorylated CD3ζ chain. 2017 Jul 1 1
7 25420722 The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model. 2015 Apr 1
8 25990959 The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway. 2015 May 19 2
9 24638062 LAPTM5 promotes lysosomal degradation of intracellular CD3ζ but not of cell surface CD3ζ. 2014 Jul 2
10 24688028 SAP facilitates recruitment and activation of LCK at NTB-A receptors during restimulation-induced cell death. 2014 May 1 1
11 25284607 CD8+ T-cell recognition of a synthetic epitope formed by t-butyl modification. 2014 Oct 5 1
12 25482031 Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation. 2014 Dec 8 2
13 25492967 The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. 2014 Dec 9 1
14 23240581 The membrane adaptor LAT is proteolytically cleaved following Fas engagement in a tyrosine phosphorylation-dependent fashion. 2013 Mar 15 2
15 23555234 Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity. 2013 2
16 23580664 The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor. 2013 May 23 2
17 23686495 GB virus C particles inhibit T cell activation via envelope E2 protein-mediated inhibition of TCR signaling. 2013 Jun 15 1
18 23874337 Centrosome polarization in T cells: a task for formins. 2013 1
19 23880762 Mitochondria-derived hydrogen peroxide selectively enhances T cell receptor-initiated signal transduction. 2013 Sep 6 2
20 23901140 The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76. 2013 Jul 30 3
21 22020291 Development of unique antibodies directed against each of the six different phosphotyrosine residues within the T cell receptor CD3ζ chain. 2012 Jan 31 3
22 22674786 TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues. 2012 Sep 2
23 22935418 Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolonged STAT activation through autocrine/paracrine stimulation in human primary T cells. 2012 Sep 21 1
24 20940326 Serine residues in the LAT adaptor are essential for TCR-dependent signal transduction. 2011 Jan 1
25 21167217 The effects of membrane compartmentalization of csk on TCR signaling. 2011 Feb 3
26 21189249 T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component. 2011 Mar 4 3
27 20028775 The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems. 2010 Apr 3
28 20381867 T cell receptor activation leads to two distinct phases of Pyk2 activation and actin cytoskeletal rearrangement in human T cells. 2010 May 1
29 21152094 T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells. 2010 Nov 30 4
30 19192391 PKD2 interacts with Lck and regulates NFAT activity in T cells. 2009 Jan 31 1
31 19201869 Genetically encoded Förster resonance energy transfer sensors for the conformation of the Src family kinase Lck. 2009 Feb 15 1
32 19265538 Alterations of T cell activation signalling and cytokine production by postmenopausal estrogen levels. 2009 Mar 5 2
33 19609962 Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways. 2009 Jul 4
34 19672294 Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity. 2009 Aug 12 1
35 18056706 Regulation of FynT function by dual domain docking on PAG/Cbp. 2008 Feb 1 1
36 18457880 TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses. 2008 Jun 1
37 18619870 A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation. 2008 Jul 18 1
38 17353368 A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76. 2007 Mar 19 1
39 17420479 SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK. 2007 Apr 17 2
40 17464179 CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta. 2007 Apr 30 1
41 17579069 Identification of a novel lipid raft-targeting motif in Src homology 2-containing phosphatase 1. 2007 Jul 1 2
42 16257509 Lck couples Shc to TCR signaling. 2006 Aug 1
43 16751250 Ligand detection and discrimination by spatial relocalization: A kinase-phosphatase segregation model of TCR activation. 2006 Sep 1 2
44 16980618 Persistence of cooperatively stabilized signaling clusters drives T-cell activation. 2006 Oct 2
45 16984412 Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing suppressor of cytokine signalling-1 (SOCS-1). 2006 Oct 1
46 15558067 Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton. 2005 Jan 1
47 15572591 Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. 2005 Mar 15 2
48 15944285 Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation. 2005 Jun 15 1
49 16014381 Cold-induced coalescence of T-cell plasma membrane microdomains activates signalling pathways. 2005 Jul 15 1
50 16081782 Redox equilibrium in mucosal T cells tunes the intestinal TCR signaling threshold. 2005 Aug 15 2