Title : Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity.

Pub. Date : 2009 Aug 12

PMID : 19672294






1 Functional Relationships(s)
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1 CONCLUSIONS/SIGNIFICANCE: We propose here a model in which Vav functions primarily as a tyrosine phosphorylated linker-protein for TCR activation of T cells. Tyrosine T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens