Title : Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells.

Pub. Date : 2021 May

PMID : 33609744






1 Functional Relationships(s)
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1 PI3K inhibition also affected the S1P receptors and gene expression of enzymes such as the dihydroceramide delta 4 desaturase (DEGS1) and sphingosine kinase 1 (SK1) in the de novo sphingolipid pathway. Sphingolipids delta 4-desaturase, sphingolipid 1 Homo sapiens