Title : Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression.

Pub. Date : 2012 Aug

PMID : 22628619






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Lipidomic analysis of distribution and speciation of multiple lipid classes indicates an increase in phospholipids in SPTLC123-silenced cells, whereas DEGS1 depletion leads to the accumulation of sphingolipid intermediates, free fatty acids, and diacylglycerol. Sphingolipids delta 4-desaturase, sphingolipid 1 Homo sapiens