Title : Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose.

Pub. Date : 2006 Apr 7

PMID : 16452468






2 Functional Relationships(s)
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1 One of the biochemical mechanisms activated by excess glucose is the polyol pathway, the key enzyme of which, aldose reductase, transforms d-glucose into d-sorbitol, leading to imbalances of intracellular homeostasis. Glucose aldo-keto reductase family 1 member B Homo sapiens
2 One of the biochemical mechanisms activated by excess glucose is the polyol pathway, the key enzyme of which, aldose reductase, transforms d-glucose into d-sorbitol, leading to imbalances of intracellular homeostasis. Glucose aldo-keto reductase family 1 member B Homo sapiens