| 1 |
34654938 | Generation of Caco-2 cells stably expressing CYP3A4·POR·UGT1A1 and CYP3A4·POR·UGT1A1*6 using a PITCh system. | 2022 Feb |
1 |
| 2 |
33615175 | Identification of Novel UGT1A1 Variants Including UGT1A1 454C>A through the Genotyping of Healthy Participants of the HPTN 077 Study. | 2021 Feb 12 |
1 |
| 3 |
33995076 | Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes. | 2021 |
2 |
| 4 |
31525573 | Determination of raltegravir and raltegravir glucuronide in human plasma and urine by LC-MS/MS with application in a maternal-fetal pharmacokinetic study. | 2020 Jan 5 |
2 |
| 5 |
28891378 | In vitro inhibition of human UGT isoforms by ritonavir and cobicistat. | 2018 Aug |
1 |
| 6 |
29743555 | Impact of UGT1A1 polymorphisms on Raltegravir and its glucuronide plasma concentrations in a cohort of HIV-1 infected patients. | 2018 May 9 |
1 |
| 7 |
30237061 | The roles of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated proteins (MRPs/ABCCs) in the excretion of cycloicaritin-3-O-glucoronide in UGT1A1-overexpressing HeLa cells. | 2018 Dec 25 |
1 |
| 8 |
27908259 | A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays. | 2017 |
1 |
| 9 |
26758854 | Efflux Transport Characterization of Resveratrol Glucuronides in UDP-Glucuronosyltransferase 1A1 Transfected HeLa Cells: Application of a Cellular Pharmacokinetic Model to Decipher the Contribution of Multidrug Resistance-Associated Protein 4. | 2016 Apr |
1 |
| 10 |
26833852 | Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway. | 2016 Sep |
4 |
| 11 |
27325020 | In vitro glucuronidation of methyl gallate and pentagalloyl glucopyranose by liver microsomes. | 2016 Aug |
1 |
| 12 |
27832172 | Regioselective Glucuronidation of Diosmetin and Chrysoeriol by the Interplay of Glucuronidation and Transport in UGT1A9-Overexpressing HeLa Cells. | 2016 |
1 |
| 13 |
25595598 | Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide. | 2015 Apr |
1 |
| 14 |
26632182 | Estimating the Differences of UGT1A1 Activity in Recombinant UGT1A1 Enzyme, Human Liver Microsomes and Rat Liver Microsome Incubation Systems in Vitro. | 2015 |
1 |
| 15 |
23888985 | Comparing the glucuronidation capacity of the feline liver with substrate-specific glucuronidation in dogs. | 2014 Feb |
1 |
| 16 |
24752421 | Hepatic microsomal UDP-glucuronosyltransferase (UGT) activities in the microminipig. | 2014 Sep |
1 |
| 17 |
23387445 | Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line. | 2013 May |
2 |
| 18 |
23670235 | Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751. | 2013 Jul |
1 |
| 19 |
23682072 | Characterization of raloxifene glucuronidation: potential role of UGT1A8 genotype on raloxifene metabolism in vivo. | 2013 Jul |
1 |
| 20 |
23917319 | Human biotransformation of the nonnucleoside reverse transcriptase inhibitor rilpivirine and a cross-species metabolism comparison. | 2013 Oct |
1 |
| 21 |
23097198 | Polymorphisms in genes involved in the metabolism and transport of soy isoflavones affect the urinary metabolite profile in premenopausal women following consumption of a commercial soy supplement as a single bolus dose. | 2012 Dec |
1 |
| 22 |
19996319 | Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions. | 2010 Feb 5 |
1 |
| 23 |
20145913 | Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies. | 2010 Mar |
1 |
| 24 |
20397195 | Glucuronidation of zearalenone, zeranol and four metabolites in vitro: formation of glucuronides by various microsomes and human UDP-glucuronosyltransferase isoforms. | 2010 Oct |
1 |
| 25 |
21175442 | Repaglinide-gemfibrozil drug interaction: inhibition of repaglinide glucuronidation as a potential additional contributing mechanism. | 2010 Dec |
1 |
| 26 |
18098064 | Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination. | 2008 Jan |
1 |
| 27 |
18430559 | Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line. | 2008 Nov |
1 |
| 28 |
18566038 | Metabolism distribution and excretion of a matrix metalloproteinase-13 inhibitor, 4-[4-(4-fluorophenoxy)-benzenesulfonylamino]tetrahydropyran-4-carboxylic acid hydroxyamide (CP-544439), in rats and dogs: assessment of the metabolic profile of CP-544439 in plasma and urine of humans. | 2008 Sep |
1 |
| 29 |
17151191 | UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics. | 2007 Mar |
2 |
| 30 |
17875670 | In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases. | 2007 Dec |
1 |
| 31 |
16504606 | Evaluation of mutation effects on UGT1A1 activity toward 17beta-estradiol using liquid chromatography-tandem mass spectrometry. | 2006 Jun 21 |
1 |
| 32 |
16513445 | Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans. | 2006 Mar |
1 |
| 33 |
17090120 | Microsomal hydroxylation and glucuronidation of [6]-gingerol. | 2006 Nov 15 |
3 |
| 34 |
17315542 | Glucuronidation of DRF-6574, hydroxy metabolite of DRF-4367 (a novel COX-2 inhibitor) by pooled human liver, intestinal microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT1A1, 1A3 and 1A8. | 2006 Oct-Dec |
1 |
| 35 |
15930350 | A phase I pharmacologic and pharmacogenetic trial of sequential 24-hour infusion of irinotecan followed by leucovorin and a 48-hour infusion of fluorouracil in adult patients with solid tumors. | 2005 Jun 1 |
1 |
| 36 |
16019265 | Long-term correction of hyperbilirubinemia in the Gunn rat by repeated intravenous delivery of naked plasmid DNA into muscle. | 2005 Nov |
1 |
| 37 |
14744946 | Involvement of human hepatic UGT1A1, UGT2B4, and UGT2B7 in the glucuronidation of carvedilol. | 2004 Feb |
1 |
| 38 |
14977865 | Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). | 2004 Mar |
1 |
| 39 |
15684703 | Nonviral gene transfer into liver and muscle for treatment of hyperbilirubinemia in the gunn rat. | 2004 Dec |
1 |
| 40 |
12867491 | Glucuronidation of HMR1098 in human microsomes: evidence for the involvement of UGT1A1 in the formation of S-glucuronides. | 2003 Aug |
1 |
| 41 |
11950779 | Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. | 2002 May |
1 |
| 42 |
12185559 | Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy. | 2002 Aug |
1 |
| 43 |
11038168 | The specificity of glucuronidation of entacapone and tolcapone by recombinant human UDP-glucuronosyltransferases. | 2000 Nov |
1 |
| 44 |
8806713 | The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1. | 1996 Aug 1 |
1 |