Title : Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751.

Pub. Date : 2013 Jul

PMID : 23670235






1 Functional Relationships(s)
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1 RESULTS: UGT1A1, UGT1A4, UGT1A8, UGT2B7, and SULT1A1 were found to be involved in the formation of inactive ABT-751 glucuronide (ABT-751G) and sulfate (ABT-751S). Glucuronides UDP glucuronosyltransferase family 1 member A1 Homo sapiens