Title : Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes.

Pub. Date : 2021

PMID : 33995076






2 Functional Relationships(s)
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1 PRH exposure also significantly increased labetalol metabolism to its UGT1A1-derived glucuronide metabolite in a concentration-dependent manner, which positively correlated with PRH-induced changes in UGT1A1 protein concentrations. Glucuronides UDP glucuronosyltransferase family 1 member A1 Homo sapiens
2 PRH exposure also significantly increased labetalol metabolism to its UGT1A1-derived glucuronide metabolite in a concentration-dependent manner, which positively correlated with PRH-induced changes in UGT1A1 protein concentrations. Glucuronides UDP glucuronosyltransferase family 1 member A1 Homo sapiens