Title : Synergistic anti-proliferative and pro-apoptotic activities of 5F and cisplatin in human non-small cell lung cancer NCI-H23 cells.

Pub. Date : 2017 Nov

PMID : 29098029






1 Functional Relationships(s)
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1 The results revealed that 5F and cisplatin synergistically induced apoptosis and inhibited cell growth, arrested cell cycles in the G0/G1 phase, downregulated beta-catenin, c-Myc and cyclin D1, and upregulated GSK-3beta. Cisplatin MYC proto-oncogene, bHLH transcription factor Homo sapiens