vandetanib

epidermal growth factor receptor ; Homo sapiens







155 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34551970 Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma. 2022 Feb 1
2 35330879 In silico Analysis of Publicly Available Transcriptomics Data Identifies Putative Prognostic and Therapeutic Molecular Targets for Papillary Thyroid Carcinoma. 2022 1
3 35331723 Novel vandetanib derivative inhibited proliferation and promoted apoptosis of cancer cells under normoxia and hypoxia. 2022 May 5 1
4 33296710 Inhibitory effects of vandetanib on creatinine transport via renal organic cation transporter OCT2. 2021 Mar 1 2
5 33721621 Safety and activity of vandetanib in combination with everolimus in patients with advanced solid tumors: a phase I study. 2021 Apr 4
6 33923880 Apoferritin/Vandetanib Association Is Long-Term Stable But Does Not Improve Pharmacological Properties of Vandetanib. 2021 Apr 20 2
7 33929994 Vandetanib-eluting radiopaque beads for chemoembolization: physicochemical evaluation and biological activity of vandetanib in hypoxia. 2021 Oct 1 2
8 34981062 Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice. 2021 Dec 20 2
9 32336008 A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin. 2020 Aug 1
10 32800552 Vandetanib inhibits cell growth in EGFR-expressing cutaneous squamous cell carcinoma. 2020 Oct 20 4
11 30860683 Tyrosine kinase inhibitors vandetanib, lenvatinib and cabozantinib modulate oxidation of an anticancer agent ellipticine catalyzed by cytochromes P450 in vitro. 2019 Feb 1
12 31233590 Vandetanib photoinduced cutaneous toxicities. 2019 May 1
13 31299389 Vandetanib sensitizes head and neck squamous cell carcinoma to photodynamic therapy through modulation of EGFR-dependent DNA repair and the tumour microenvironment. 2019 Sep 3
14 29363191 Investigation of the binding characteristics between ligands and epidermal growth factor receptor by cell membrane chromatography. 2018 Jun 2
15 29517106 Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo. 2018 May 1
16 30321910 Epidermal growth factor receptor blockers for the treatment of ovarian cancer. 2018 Oct 16 1
17 30555244 Vandetanib (ZD6474) induces antiangiogenesis through mTOR-HIF-1 alpha-VEGF signaling axis in breast cancer cells. 2018 2
18 26986978 Induction Therapy for Locally Advanced, Resectable Esophagogastric Cancer: A Phase I Trial of Vandetanib (ZD6474), Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiotherapy Followed by Resection. 2017 Aug 1
19 28132823 Preparation and characterisation of vandetanib-eluting radiopaque beads for locoregional treatment of hepatic malignancies. 2017 Apr 1 2
20 28259610 Vandetanib plus gemcitabine versus placebo plus gemcitabine in locally advanced or metastatic pancreatic carcinoma (ViP): a prospective, randomised, double-blind, multicentre phase 2 trial. 2017 Apr 1
21 25352401 Phase I study of vandetanib with radiation therapy with or without cisplatin in locally advanced head and neck squamous cell carcinoma. 2016 Mar 2
22 26832794 EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib. 2016 Mar 3
23 27250896 Novel agents in second-line therapy for EGFR wild-type Advanced Non-Small-Cell Lung Cancer. 2016 May 1
24 27711083 RADVAN: a randomised phase 2 trial of WBRT plus vandetanib for melanoma brain metastases - results and lessons learnt. 2016 Nov 8 1
25 27798882 The Significant Role of Cyclin D1 in the Synergistic Growth-inhibitory Effect of Combined Therapy of Vandetanib with 5-Fluorouracil for Gastric Cancer. 2016 Oct 2
26 27983649 Design and Synthesis of Vandetanib Derivatives Containing Nitroimidazole Groups as Tyrosine Kinase Inhibitors in Normoxia and Hypoxia. 2016 Dec 14 2
27 25503302 Vandetanib plus sirolimus in adults with recurrent glioblastoma: results of a phase I and dose expansion cohort study. 2015 Feb 1
28 25887790 Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment. 2015 Apr 3 2
29 25910950 A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients. 2015 Aug 15 1
30 26050198 ZD6474, a new treatment strategy for human osteosarcoma, and its potential synergistic effect with celecoxib. 2015 Aug 28 3
31 26170630 Selective use of vandetanib in the treatment of thyroid cancer. 2015 1
32 24412287 Targeting the epidermal growth factor receptor for head and neck cancer chemoprevention. 2014 Oct 1
33 24502390 Vandetanib for the treatment of thyroid cancer: an update. 2014 Mar 1
34 24671507 A randomized phase II efficacy and safety study of vandetanib (ZD6474) in combination with bicalutamide versus bicalutamide alone in patients with chemotherapy naïve castration-resistant prostate cancer. 2014 Aug 1
35 24709487 Randomised phase II study of docetaxel plus vandetanib versus docetaxel followed by vandetanib in patients with persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: SWOG S0904. 2014 Jun 1
36 24924416 Randomised, phase II, placebo-controlled, trial of fulvestrant plus vandetanib in postmenopausal women with bone only or bone predominant, hormone-receptor-positive metastatic breast cancer (MBC): the OCOG ZAMBONEY study. 2014 Jul 1
37 25057173 EGFR biomarkers predict benefit from vandetanib in combination with docetaxel in a randomized phase III study of second-line treatment of patients with advanced non-small cell lung cancer. 2014 Oct 5
38 25089348 Vandetanib as a potential treatment for breast cancer. 2014 Sep 1
39 25117183 Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine. 2014 Sep 2
40 22608542 Contrasted effects of the multitarget TKi vandetanib on docetaxel-sensitive and docetaxel-resistant prostate cancer cell lines. 2013 Nov 1
41 23177099 Chemotherapy plus Vandetanib or chemotherapy alone in advanced non-small cell lung cancer: a meta-analysis of four randomised controlled trials. 2013 Jan 1
42 23202050 Vandetanib and the management of advanced medullary thyroid cancer. 2013 Jan 1
43 23231950 Vandetanib for the treatment of medullary thyroid cancer. 2013 Feb 1 3
44 23274758 Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency. 2013 Feb 15 4
45 23487538 Toxic cardiomyopathy leading to fatal acute cardiac failure related to vandetanib: a case report with histopathological analysis. 2013 Jun 1
46 23584298 Clinical and biomarker outcomes of the phase II vandetanib study from the BATTLE trial. 2013 May 3
47 23640345 Vandetanib: a novel targeted therapy for the treatment of metastatic or locally advanced medullary thyroid cancer. 2013 May 15 1
48 23799852 Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma. 2013 Jul 9 2
49 24005613 Addition of vandetanib to pegylated liposomal doxorubicin (PLD) in patients with recurrent ovarian cancer. A randomized phase I/II study of the AGO Study Group (AGO-OVAR 2.13). 2013 Dec 1
50 21046425 Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents. 2012 Apr 1