Pub. Date : 2016 Mar
PMID : 26832794
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib. | vandetanib | epidermal growth factor receptor | Homo sapiens |
| 2 | The effect of the TKI vandetanib on proliferation and tumor growth response of MCF-7 cells was dependent upon expression of TFAP2C, and dual KD of RET and EGFR eliminated the effects of vandetanib. | vandetanib | epidermal growth factor receptor | Homo sapiens |
| 3 | Response to vandetanib was mediated through the TFAP2C target genes EGFR and RET. | vandetanib | epidermal growth factor receptor | Homo sapiens |