Curcumin

epidermal growth factor receptor ; Homo sapiens







61 Article(s)
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Pub. Year
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1 34994998 Curcumin suppresses cell proliferation and triggers apoptosis in vemurafenib-resistant melanoma cells by downregulating the EGFR signaling pathway. 2022 Apr 3
2 33003239 Curcumin Promotes Collagen Type I, Keratinocyte Growth Factor-1, and Epidermal Growth Factor Receptor Expressions in the In Vitro Wound Healing Model of Human Gingival Fibroblasts. 2021 Feb 6
3 34804186 Bioinformatics Analysis to Screen Key Targets of Curcumin against Colorectal Cancer and the Correlation with Tumor-Infiltrating Immune Cells. 2021 2
4 31545905 Effects of somatostatin, curcumin, and quercetin on the fatty acid profile of breast cancer cell membranes. 2020 Mar 1
5 31793078 Curcumin enhances radiosensitization of nasopharyngeal carcinoma by regulating circRNA network. 2020 Feb 2
6 32691972 The in vivo preventive and therapeutic properties of curcumin in bile reflux-related oncogenesis of the hypopharynx. 2020 Sep 1
7 33178666 Enhancing Bioavailability and Stability of Curcumin Using Solid Lipid Nanoparticles (CLEN): A Covenant for Its Effectiveness. 2020 1
8 33246423 A novel TGF-β receptor II mutation (I227T/N236D) promotes aggressive phenotype of oral squamous cell carcinoma via enhanced EGFR signaling. 2020 Nov 27 2
9 30542713 Curcumin attenuates hyperglycemia-driven EGF-induced invasive and migratory abilities of pancreatic cancer via suppression of the ERK and AKT pathways. 2019 Jan 3
10 30899155 Molecular designing, virtual screening and docking study of novel curcumin analogue as mutation (S769L and K846R) selective inhibitor for EGFR. 2019 Mar 1
11 31196210 Curcumin overcome primary gefitinib resistance in non-small-cell lung cancer cells through inducing autophagy-related cell death. 2019 Jun 13 4
12 31289524 Radiosensitization effects of curcumin plus cisplatin on non-small cell lung cancer A549 cells. 2019 Jul 1
13 31432177 Curcumin inhibits cell proliferation and migration in NSCLC through a synergistic effect on the TLR4/MyD88 and EGFR pathways. 2019 Nov 3
14 29157028 Enhanced selective cellular uptake and cytotoxicity of epidermal growth factor-conjugated liposomes containing curcumin on EGFR-overexpressed pancreatic cancer cells. 2018 Sep 4
15 29445279 EGFR-targeted photodynamic therapy by curcumin-encapsulated chitosan/TPP nanoparticles. 2018 2
16 29620257 Curcumin suppresses MUC5AC production via interfering with the EGFR signaling pathway. 2018 Jul 7
17 29700289 RCP induces FAK phosphorylation and ovarian cancer cell invasion with inhibition by curcumin. 2018 Apr 27 2
18 29805641 Targeted therapy of triple negative MDA-MB-468 breast cancer with curcumin delivered by epidermal growth factor-conjugated phospholipid nanoparticles. 2018 Jun 1
19 30214301 A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction. 2018 1
20 30333889 Synergistic inhibitory effects of cetuximab and curcumin on human cisplatin-resistant oral cancer CAR cells through intrinsic apoptotic process. 2018 Nov 1
21 28117012 Current Status and Perspectives Regarding the Therapeutic Potential of Targeting EGFR Pathway by Curcumin in Lung Cancer. 2017 1
22 28122302 Co-delivery of docetaxel and curcumin prodrug via dual-targeted nanoparticles with synergistic antitumor activity against prostate cancer. 2017 Apr 1
23 28286519 ErbB Proteins as Molecular Target of Dietary Phytochemicals in Malignant Diseases. 2017 1
24 29052674 EGFR-targeting PLGA-PEG nanoparticles as a curcumin delivery system for breast cancer therapy. 2017 Nov 2 2
25 26505786 Combinatorial Effects of Curcumin with an Anti-Neoplastic Agent on Head and Neck Squamous Cell Carcinoma Through the Regulation of EGFR-ERK1/2 and Apoptotic Signaling Pathways. 2016 Jan 11 2
26 25753330 Novel curcumin analogs to overcome EGFR-TKI lung adenocarcinoma drug resistance and reduce EGFR-TKI-induced GI adverse effects. 2015 Apr 1 6
27 26468449 Colon cancer and the epidermal growth factor receptor: Current treatment paradigms, the importance of diet, and the role of chemoprevention. 2015 Oct 10 1
28 24318305 Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling. 2014 Aug 2
29 24445050 Down-regulation of epidermal growth factor receptor by curcumin-induced UBE1L in human bronchial epithelial cells. 2014 Feb 5
30 24491504 Ensemble docking and molecular dynamics identify knoevenagel curcumin derivatives with potent anti-EGFR activity. 2014 Apr 10 3
31 24508477 Curcumin and (-)-epigallocatechin-3-gallate attenuate acrylamide-induced proliferation in HepG2 cells. 2014 Apr 1
32 25400722 Curcumin inhibits oral squamous cell carcinoma proliferation and invasion via EGFR signaling pathways. 2014 8
33 23234806 A novel curcumin-based vaginal cream Vacurin selectively eliminates apposed human cervical cancer cells. 2013 Apr 1
34 23245570 Design, synthesis and molecular docking of α,β-unsaturated cyclohexanone analogous of curcumin as potent EGFR inhibitors with antiproliferative activity. 2013 Jan 15 2
35 23880083 Exploring pyrimidine-substituted curcumin analogues: design, synthesis and effects on EGFR signaling. 2013 Sep 1 2
36 24512728 Curcumin lowers erlotinib resistance in non-small cell lung carcinoma cells with mutated EGF receptor. 2013 3
37 21567511 Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells. 2012 Jan 2
38 22489192 Curcumin: updated molecular mechanisms and intervention targets in human lung cancer. 2012 3
39 23023821 Curcumin induces apoptosis of triple-negative breast cancer cells by inhibition of EGFR expression. 2012 Dec 1
40 23194063 Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs. 2012 Nov 30 2
41 21858220 Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy. 2011 5
42 21859497 Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy. 2011 Aug 23 1
43 20332435 Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R. 2010 Feb 1
44 20407012 Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells. 2010 May 6
45 19448398 Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression. 2009 Jul 3
46 19956394 Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX. 2009 Dec 2
47 17918158 Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R. 2008 Jan 15 1
48 18214481 Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells. 2008 Oct 2
49 18332871 Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells. 2008 May 4
50 18719366 Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome. 2008 Sep 1