Pub. Date : 2013
PMID : 24512728
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin lowers erlotinib resistance in non-small cell lung carcinoma cells with mutated EGF receptor. | Curcumin | epidermal growth factor receptor | Homo sapiens |
| 2 | Furthermore, curcumin significantly increased the cytotoxicity of erlotinib to erlotinib-resistant NSCLC cells, enhanced erlotinib-induced apoptosis, downregulated the expressions of EGFR, p-EGFR, and survivin, and inhibited the NF-kappaB activation in erlotinib-resistant NSCLC cells. | Curcumin | epidermal growth factor receptor | Homo sapiens |
| 3 | Furthermore, curcumin significantly increased the cytotoxicity of erlotinib to erlotinib-resistant NSCLC cells, enhanced erlotinib-induced apoptosis, downregulated the expressions of EGFR, p-EGFR, and survivin, and inhibited the NF-kappaB activation in erlotinib-resistant NSCLC cells. | Curcumin | epidermal growth factor receptor | Homo sapiens |