Pub. Date : 2015 Apr 1
PMID : 25753330
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Novel curcumin analogs to overcome EGFR-TKI lung adenocarcinoma drug resistance and reduce EGFR-TKI-induced GI adverse effects. | Curcumin | epidermal growth factor receptor | Homo sapiens |
| 2 | Novel curcumin analogs to overcome EGFR-TKI lung adenocarcinoma drug resistance and reduce EGFR-TKI-induced GI adverse effects. | Curcumin | epidermal growth factor receptor | Homo sapiens |
| 3 | Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR. | Curcumin | epidermal growth factor receptor | Homo sapiens |
| 4 | Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR. | Curcumin | epidermal growth factor receptor | Homo sapiens |
| 5 | Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR. | Curcumin | epidermal growth factor receptor | Homo sapiens |
| 6 | Among all evaluated curcumin derivatives, compound 2 showed the best inhibitory effects on both wild-type and mutant EGFR by efficiently inducing gefitinib-insensitive EGFR degradation. | Curcumin | epidermal growth factor receptor | Homo sapiens |