| 1 |
32739400 | Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing. | 2020 Oct 1 |
2 |
| 2 |
31772931 | Research Progress of the Functional Role of ACK1 in Breast Cancer. | 2019 |
2 |
| 3 |
31819114 | Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen. | 2019 Dec 9 |
2 |
| 4 |
31845724 | The non-receptor tyrosine kinase ACK: regulatory mechanisms, signalling pathways and opportunities for attACKing cancer. | 2019 Dec 20 |
2 |
| 5 |
28921811 | A role for the non-receptor tyrosine kinase ACK1 in TNF-alpha-mediated apoptosis and proliferation in human intestinal epithelial caco-2 cells. | 2018 Sep |
1 |
| 6 |
30018082 | Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia. | 2018 Jul 17 |
2 |
| 7 |
28609657 | ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. | 2017 Jun 12 |
2 |
| 8 |
25257795 | PDGFR-β-activated ACK1-AKT signaling promotes glioma tumorigenesis. | 2015 Apr 15 |
1 |
| 9 |
25347744 | ACK1/TNK2 tyrosine kinase: molecular signaling and evolving role in cancers. | 2015 Aug 6 |
2 |
| 10 |
25678401 | ACK1 promotes gastric cancer epithelial-mesenchymal transition and metastasis through AKT-POU2F1-ECD signalling. | 2015 Jun |
1 |
| 11 |
25950519 | Mutation of androgen receptor N-terminal phosphorylation site Tyr-267 leads to inhibition of nuclear translocation and DNA binding. | 2015 |
2 |
| 12 |
25148682 | ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1. | 2014 Oct 10 |
1 |
| 13 |
25427824 | Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1. | 2014 Nov 26 |
1 |
| 14 |
23597703 | ACK1 tyrosine kinase: targeted inhibition to block cancer cell proliferation. | 2013 Sep 28 |
1 |
| 15 |
22307544 | PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics. | 2012 Sep |
2 |
| 16 |
22322295 | Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. | 2012 Apr |
1 |
| 17 |
22566699 | Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer. | 2012 Jun 22 |
3 |
| 18 |
22952966 | Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation. | 2012 |
2 |
| 19 |
21129804 | A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients. | 2011 Apr |
1 |
| 20 |
20383201 | Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases. | 2010 Jun 3 |
4 |
| 21 |
20570899 | Compensatory upregulation of tyrosine kinase Etk/BMX in response to androgen deprivation promotes castration-resistant growth of prostate cancer cells. | 2010 Jul 1 |
1 |
| 22 |
20623637 | Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity. | 2010 Sep 1 |
1 |
| 23 |
19366686 | The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration. | 2009 Jun 5 |
1 |
| 24 |
17182860 | Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation. | 2007 Mar |
1 |
| 25 |
17494760 | Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation. | 2007 May 15 |
8 |
| 26 |
16777958 | Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli. | 2006 Jun 27 |
3 |
| 27 |
16257963 | Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinase. | 2005 Dec 23 |
1 |
| 28 |
16288044 | Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox. | 2005 Nov 15 |
5 |
| 29 |
14506255 | Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck. | 2003 Nov 28 |
4 |
| 30 |
11087735 | Stimulation of M3 muscarinic receptors induces phosphorylation of the Cdc42 effector activated Cdc42Hs-associated kinase-1 via a Fyn tyrosine kinase signaling pathway. | 2001 Feb 23 |
3 |
| 31 |
10652228 | Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation. | 2000 Feb 5 |
3 |
| 32 |
10882715 | Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1. | 2000 Sep 22 |
3 |
| 33 |
10587647 | Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas. | 1999 Dec |
1 |
| 34 |
8647288 | Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation. | 1996 May 20 |
4 |