Title : Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli.

Pub. Date : 2006 Jun 27

PMID : 16777958






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Upon cell stimulation with EGF or PDGF, Ack is tyrosine-phosphorylated and recruited to activated EGF or PDGF receptors, respectively. Tyrosine tyrosine kinase non receptor 2 Homo sapiens
2 A pool of endogenous Ack molecules is constitutively tyrosine-phosphorylated, even in starved cells. Tyrosine tyrosine kinase non receptor 2 Homo sapiens
3 Moreover, tyrosine-phosphorylated Ack forms a stable complex with the adapter protein Nck via its SH2 domain. Tyrosine tyrosine kinase non receptor 2 Homo sapiens