Title : Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing.

Pub. Date : 2020 Oct 1

PMID : 32739400






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The protein kinase TNK2 (ACK1) is an emerging drug target for a variety of indications, in particular for cancer where it plays a key role transmitting cell survival, growth and proliferative signals via modification of multiple downstream effectors by unique tyrosine phosphorylation events. Tyrosine tyrosine kinase non receptor 2 Homo sapiens
2 The protein kinase TNK2 (ACK1) is an emerging drug target for a variety of indications, in particular for cancer where it plays a key role transmitting cell survival, growth and proliferative signals via modification of multiple downstream effectors by unique tyrosine phosphorylation events. Tyrosine tyrosine kinase non receptor 2 Homo sapiens