Title : ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1.

Pub. Date : 2014 Oct 10

PMID : 25148682






1 Functional Relationships(s)
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1 We report that ACK1 phosphorylates the ER co-activator, KDM3A, a H3K9 demethylase, at an evolutionary conserved tyrosine 1114 site in a heregulin-dependent manner, even in the presence of tamoxifen. Tyrosine tyrosine kinase non receptor 2 Homo sapiens