Title : Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation.

Pub. Date : 2000 Feb 5

PMID : 10652228






3 Functional Relationships(s)
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1 Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation. Tyrosine tyrosine kinase non receptor 2 Homo sapiens
2 When transiently coexpressed with the activated form of the non-receptor tyrosine kinase ACK1, a downstream target of Cdc42, Dbl became tyrosine-phosphorylated. Tyrosine tyrosine kinase non receptor 2 Homo sapiens
3 Moreover, accumulation of the GTP-bound form of Rho and Rac within the cell paralleled ACK-1-dependent tyrosine phosphorylation of Dbl. Tyrosine tyrosine kinase non receptor 2 Homo sapiens