2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

AKT serine/threonine kinase 1 ; Homo sapiens







87 Article(s)
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1 34875308 Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK. 2022 Feb 1
2 33242203 Extracellular Vesicles Derived from Intermittent Hypoxia-Treated Red Blood Cells Impair Endothelial Function Through Regulating eNOS Phosphorylation and ET-1 Expression. 2021 Oct 1
3 33273969 Role of the stromal cell derived factor-1 in the biological functions of endothelial progenitor cells and its underlying mechanisms. 2021 Jan 1
4 34184076 TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway. 2021 Aug 1
5 35111045 An ApoA-I Mimic Peptide of 4F Promotes SDF-1α Expression in Endothelial Cells Through PI3K/Akt/ERK/HIF-1α Signaling Pathway. 2021 1
6 32174780 Suppressive effects of S100A8 and S100A9 on neutrophil apoptosis by cytokine release of human bronchial epithelial cells in asthma. 2020 1
7 32392915 Heat shock protein 90 inhibitor AUY922 attenuates platelet-derived growth factor-BB-induced migration and proliferation of vascular smooth muscle cells. 2020 May 1 1
8 32395075 Heat shock protein 90 inhibitor AUY922 attenuates platelet-derived growth factor-BB-induced migration and proliferation of vascular smooth muscle cells. 2020 May 1 1
9 32630394 Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells. 2020 Jun 25 1
10 32751124 3D Bioprinted Osteogenic Tissue Models for In Vitro Drug Screening. 2020 Jul 29 1
11 31076999 Naringenin Inhibit the Hydrogen Peroxide-Induced SH-SY5Y Cells Injury Through Nrf2/HO-1 Pathway. 2019 Nov 1
12 31088549 Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK-3β signaling pathway. 2019 May 14 1
13 31270642 Decellularized and solubilized pancreatic stroma promotes the in vitro proliferation, migration and differentiation of BMSCs into IPCs. 2019 Sep 1
14 29964149 PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia. 2018 Oct 1
15 30622592 Neuroprotective Effects of Gagam-Sipjeondaebo-Tang, a Novel Herbal Formula, against MPTP-Induced Parkinsonian Mice and MPP+-Induced Cell Death in SH-SY5Y Cells. 2018 1
16 28356980 Regulation of cell migration via the EGFR signaling pathway in oral squamous cell carcinoma cells. 2017 Feb 1
17 28381122 Argon Exposure Induces Postconditioning in Myocardial Ischemia-Reperfusion. 2017 Nov 1
18 28612103 Dihydromyricetin protects human umbilical vein endothelial cells from injury through ERK and Akt mediated Nrf2/HO-1 signaling pathway. 2017 Aug 1
19 28639894 Deregulated expression of Cdc6 as BCR/ABL-dependent survival factor in chronic myeloid leukemia cells. 2017 Jun 1
20 26915319 Inhibitory effect of luteolin on the proliferation of human breast cancer cell lines induced by epidermal growth factor. 2016 Feb 25 1
21 26923291 SIRT1 mediates Sphk1/S1P-induced proliferation and migration of endothelial cells. 2016 May 1
22 27018134 Attenuative role of mangiferin in oxidative stress-mediated liver dysfunction in arsenic-intoxicated murines. 2016 Sep 10 1
23 27107990 COMP-Ang1 enhances DNA synthesis and cell cycle progression in human periodontal ligament cells via Tie2-mediated phosphorylation of PI3K/Akt and MAPKs. 2016 May 1
24 27240591 S100A16 promotes cell proliferation and metastasis via AKT and ERK cell signaling pathways in human prostate cancer. 2016 Sep 1
25 27802437 Valproic Acid Promotes Human Glioma U87 Cells Apoptosis and Inhibits Glycogen Synthase Kinase-3β Through ERK/Akt Signaling. 2016 1
26 25638063 Octacosanol enhances the proliferation and migration of human umbilical vein endothelial cells via activation of the PI3K/Akt and MAPK/Erk pathways. 2015 Mar 1
27 25638174 Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer. 2015 Feb 1 1
28 23604952 Platelet-rich plasma releasate promotes angiogenesis in vitro and in vivo. 2014 Jun 1
29 24247909 Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma. 2014 Jan 1
30 24394624 Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells. 2014 Jun 2
31 24617901 IKVAV regulates ERK1/2 and Akt signalling pathways in BMMSC population growth and proliferation. 2014 Apr 1
32 24805814 BMP9 inhibits proliferation and metastasis of HER2-positive SK-BR-3 breast cancer cells through ERK1/2 and PI3K/AKT pathways. 2014 1
33 25034934 FTY720 attenuates hypoxia-reoxygenation-induced apoptosis in cardiomyocytes. 2014 Oct 1
34 25206916 Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury and neurite outgrowth. 2014 May 1 1
35 22716951 Maslinic acid inhibits the metastatic capacity of DU145 human prostate cancer cells: possible mediation via hypoxia-inducible factor-1α signalling. 2013 Jan 28 1
36 23135225 Vaspin attenuates the apoptosis of human osteoblasts through ERK signaling pathway. 2013 Mar 1
37 23161148 Neuroprotection of interleukin-6 against NMDA-induced neurotoxicity is mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT signaling pathways. 2013 Mar 1
38 23233127 Knockdown of integrin α3β1 expression induces proliferation and migration of non-small cell lung cancer cells. 2013 Feb 1
39 23707520 FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway. 2013 Sep 1
40 23948751 Reversal of boswellic acid analog BA145 induced caspase dependent apoptosis by PI3K inhibitor LY294002 and MEK inhibitor PD98059. 2013 Dec 1
41 23950935 Mechanical stretch increases MMP-2 production in vascular smooth muscle cells via activation of PDGFR-β/Akt signaling pathway. 2013 1
42 24098385 Angiotensin II signaling in human preadipose cells: participation of ERK1,2-dependent modulation of Akt. 2013 2
43 24227918 Apelin-13 induces proliferation, migration, and collagen I mRNA expression in human RPE cells via PI3K/Akt and MEK/Erk signaling pathways. 2013 1
44 21544845 Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1α via epidermal growth factor receptor-mediated signaling pathways. 2012 Apr 1
45 22155408 Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells. 2012 Mar 5 1
46 22497886 Protease-activated receptor-2 (PAR2) mediates VEGF production through the ERK1/2 pathway in human glioblastoma cell lines. 2012 May 4 1
47 22534171 Opposite regulation by PI3K/Akt and MAPK/ERK pathways of tissue factor expression, cell-associated procoagulant activity and invasiveness in MDA-MB-231 cells. 2012 Jul 11 2
48 22908970 The proliferative effects of ghrelin on human gastric cancer AGS cells. 2012 Sep 1
49 23190603 Cordyceps militaris and mycelial fermentation induced apoptosis and autophagy of human glioblastoma cells. 2012 Nov 29 1
50 21904903 PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancer. 2011 Nov 1