Title : Valproic Acid Promotes Human Glioma U87 Cells Apoptosis and Inhibits Glycogen Synthase Kinase-3β Through ERK/Akt Signaling.

Pub. Date : 2016

PMID : 27802437






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 However, the MAPK inhibitor PD98059 and/or PI3K inhibitor LY294002 were able to antagonize the effects of VPA by abolishing ERK/Akt activations and cancelling GSK3beta suppression, thus it impaired VPA apoptosis-inducing effects on glioma cells. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one AKT serine/threonine kinase 1 Homo sapiens