Title : Mechanical stretch increases MMP-2 production in vascular smooth muscle cells via activation of PDGFR-β/Akt signaling pathway.

Pub. Date : 2013

PMID : 23950935






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 MS-enhanced MMP-2 expression and activity were inhibited by molecular inhibition of Akt using Akt siRNA as well as by PI3K/Akt inhibitors, LY293002 and AI, but not by MAPK inhibitors such as PD98059, SP600125 and SB203580. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one AKT serine/threonine kinase 1 Homo sapiens