Wortmannin

AKT serine/threonine kinase 1 ; Homo sapiens







540 Article(s)
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1 34998793 Antiandrogenic activity of Riboflavin 5'-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines. 2022 Feb 15 1
2 35063466 KIR2DL4 promotes the proliferation of RCC cell associated with PI3K/Akt signaling activation. 2022 Mar 15 1
3 35163245 Sp1 Plays a Key Role in Vasculogenic Mimicry of Human Prostate Cancer Cells. 2022 Jan 25 1
4 35165791 Transcriptomic analysis and biological evaluation reveals that LMO3 regulates the osteogenic differentiation of human adipose derived stem cells via PI3K/Akt signaling pathway. 2022 Apr 2
5 35203351 ACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells. 2022 Feb 17 2
6 33191001 Lipid raft-associated PI3K/Akt/SREBP1 signaling regulates coxsackievirus A16 (CA16) replication. 2021 Jan 1
7 33503805 Estrogen Receptor Signaling Pathways Involved in Invasion and Colony Formation of Androgen-Independent Prostate Cancer Cells PC-3. 2021 Jan 25 1
8 33506378 PI3K/AKT signaling drives titanium-induced angiogenic stimulus. 2021 Jan 27 1
9 33508440 DHEA inhibits proliferation, migration and alters mesenchymal-epithelial transition proteins through the PI3K/Akt pathway in MDA-MB-231 cells. 2021 Apr 1
10 33540491 LPAR5 promotes thyroid carcinoma cell proliferation and migration by activating class IA PI3K catalytic subunit p110β. 2021 Apr 1
11 33582643 Insight into the mechanism of tetrachlorobisphenol A (TCBPA)-induced proliferation of breast cancer cells by GPER-mediated signaling pathways. 2021 Apr 15 1
12 33807594 Neutrophil Adhesion and the Release of the Free Amino Acid Hydroxylysine. 2021 Mar 5 1
13 34015318 Methyl palmitate protects heart against ischemia/reperfusion-induced injury through G-protein coupled receptor 40-mediated activation of the PI3K/AKT pathway. 2021 Aug 15 2
14 34604387 Influences of S100A8 and S100A9 on Proliferation of Nasopharyngeal Carcinoma Cells through PI3K/Akt Signaling Pathway. 2021 2
15 34832894 Hydroquinone 5-O-Cinnamoyl Ester of Renieramycin M Suppresses Lung Cancer Stem Cells by Targeting Akt and Destabilizes c-Myc. 2021 Oct 30 2
16 31622648 Chrysoeriol mediates mitochondrial protection via PI3K/Akt pathway in MPP+ treated SH-SY5Y cells. 2020 Jan 1 1
17 31939617 Inhibition of TPA‑induced metastatic potential by morin hydrate in MCF‑7 human breast cancer cells via the Akt/GSK‑3β/c‑Fos signaling pathway. 2020 Feb 1
18 32323781 MicroRNA‑22 mediates the cisplatin resistance of osteosarcoma cells by inhibiting autophagy via the PI3K/Akt/mTOR pathway. 2020 Apr 1
19 32334286 G-5555 synergized miR-485-5p to alleviate cisplatin resistance in ovarian cancer cells via Pi3k/Akt signaling pathway. 2020 Aug 1
20 32373892 Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity. 2020 Jun 24 2
21 32394669 Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/ β-Catenin Pathway in Dermal Papilla Cells. 2020 Jul 1 1
22 32687618 ELABELA improves endothelial cell function via the ELA-APJ axis by activating the PI3K/Akt signalling pathway in HUVECs and EA.hy926 cells. 2020 Dec 1
23 32733640 PI3K/Akt and ERK1/2 Signalling Are Involved in Quercetin-Mediated Neuroprotection against Copper-Induced Injury. 2020 1
24 32781572 Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling. 2020 Aug 6 1
25 32861747 Upregulation of Akt/Raptor signaling is associated with rapamycin resistance of breast cancer cells. 2020 Oct 1 1
26 32892226 Kukoamine A Protects against NMDA-Induced Neurotoxicity Accompanied with Down-Regulation of GluN2B-Containing NMDA Receptors and Phosphorylation of PI3K/Akt/GSK-3β Signaling Pathway in Cultured Primary Cortical Neurons. 2020 Nov 1
27 33067961 [Up-Regulation of PI3K/Akt Signaling Pathway in H929 Cell Line by Doxycycline Not Beneficial to Its Anti-Myeloma Effect]. 2020 Oct 3
28 33343341 Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling. 2020 1
29 33717055 Submission for Special Issue: The Role of Platelet Activation in the Pathophysiology of HIV, Tuberculosis, and Pneumococcal Disease. Bedaquiline Suppresses ADP-Mediated Activation of Human Platelets In Vitro via Interference With Phosphatidylinositol 3-Kinase. 2020 1
30 30316647 Intracellular acidosis via activation of Akt-Girdin signaling promotes post ischemic angiogenesis during hyperglycemia. 2019 Feb 15 1
31 30449288 Leucine promotes porcine myofibre type transformation from fast-twitch to slow-twitch through the protein kinase B (Akt)/forkhead box 1 signalling pathway and microRNA-27a. 2019 Jan 1
32 30737086 PI3K inhibitors protect against glucocorticoid-induced skin atrophy. 2019 Mar 1
33 30742066 CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation. 2019 Jun 2
34 30822534 Oxibendazole induces apoptotic cell death in proliferating porcine trophectoderm and uterine luminal epithelial cells via mitochondria-mediated calcium disruption and breakdown of mitochondrial membrane potential. 2019 Jun 1
35 30838710 Insulin promotes invasion and migration of KRASG12D mutant HPNE cells by upregulating MMP-2 gelatinolytic activity via ERK- and PI3K-dependent signalling. 2019 May 1
36 30896878 Metabolic dependence of cyclosporine A on cell proliferation of human non‑small cell lung cancer A549 cells and its implication in post‑transplant malignancy. 2019 May 1
37 30920401 Fluvastatin exerts an antitumor effect in vemurafenib-resistant melanoma cells. 2019 Jun 1
38 31077466 The mechanism for differential effect of nelfinavir and indinavir on collagen metabolism in human skin fibroblasts. 2019 Jul 2
39 31173226 UBE2T promotes proliferation and regulates PI3K/Akt signaling in renal cell carcinoma. 2019 Aug 2
40 31360208 Brazilian Green Propolis Inhibits Ox-LDL-Stimulated Oxidative Stress in Human Umbilical Vein Endothelial Cells Partly through PI3K/Akt/mTOR-Mediated Nrf2/HO-1 Pathway. 2019 1
41 29054588 Titanium dioxide nanoparticles induce human eosinophil adhesion onto endothelial EA.hy926 cells via activation of phosphoinositide 3-kinase/Akt cell signalling pathway. 2018 Feb 2
42 29115459 Isolariciresinol-9'-O-α-L-arabinofuranoside protects against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells via a PI3K/Akt/Bad‑dependent pathway. 2018 Jan 1
43 29549527 In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS). 2018 May 1
44 29859204 Neuroprotective effect of zolpidem against glutamate-induced toxicity is mediated via the PI3K/Akt pathway and inhibited by PK11195. 2018 Aug 1 1
45 29916527 Mitochondrial dysfunction induces the invasive phenotype, and cell migration and invasion, through the induction of AKT and AMPK pathways in lung cancer cells. 2018 Sep 1
46 30396956 Evodiamine Suppresses Survival, Proliferation, Migration and Epithelial-Mesenchymal Transition of Thyroid Carcinoma Cells. 2018 Nov 1
47 30585261 Nitric oxide prevents H2O2-induced apoptosis in SK-N-MC human neuroblastoma cells. 2018 1
48 27683229 Rapamycin suppresses hypoxia/reoxygenation-induced islet injury by up-regulation of miR-21 via PI3K/Akt signalling pathway. 2017 Feb 1
49 28000865 PI3K inhibitor LY294002, as opposed to wortmannin, enhances AKT phosphorylation in gemcitabine-resistant pancreatic cancer cells. 2017 Feb 1
50 28176634 Targeting the Akt/PI3K Signaling Pathway as a Potential Therapeutic Strategy for the Treatment of Pancreatic Cancer. 2017 1