Title : Fluvastatin exerts an antitumor effect in vemurafenib-resistant melanoma cells.

Pub. Date : 2019 Jun

PMID : 30920401






1 Functional Relationships(s)
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1 The VR cells derived from HMY-1 and SK-MEL-28 showed constitutive activation of AKT kinase, and the specific AKT inhibitor MK-2208 or the PI3K inhibitor wortmannin increased the cellular sensitivity to vemurafenib. Wortmannin AKT serine/threonine kinase 1 Homo sapiens