Pub. Date : 2015 Dec 15
PMID : 26585822
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genetic variations in the PI3K/AKT pathway predict platinum-based neoadjuvant chemotherapeutic sensitivity in squamous cervical cancer. | Platinum | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | The PI3K/Akt pathway plays a role in chemoresistance to platinum-based neoadjuvant chemotherapy (NAC). | Platinum | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | The objective of this study was to evaluate the association between genetic polymorphisms in the PI3K/Akt pathway and chemotherapeutic outcomes following platinum-based NAC in Northwestern Chinese Han patients with squamous cervical cancer (SCC). | Platinum | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | SIGNIFICANCE: The findings from this study demonstrate that genetic polymorphisms in the PI3K/Akt pathway are associated with sensitivity to platinum-based chemotherapy in SCC patients. | Platinum | AKT serine/threonine kinase 1 | Homo sapiens |