Title : Phospho-Akt overexpression in non-small cell lung cancer confers significant stage-independent survival disadvantage.

Pub. Date : 2004 Oct 15

PMID : 15501963






1 Functional Relationships(s)
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1 In cell lines derived from human non-small cell lung cancers (NSCLCs), Akt has been shown to confer chemoresistance by inhibition of apoptosis in response to different chemotherapeutic agents including platinum-based agents, which are often the first-line therapy for NSCLCs. Platinum AKT serine/threonine kinase 1 Homo sapiens