Title : E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells.

Pub. Date : 2012 Apr 5

PMID : 22322152






1 Functional Relationships(s)
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1 Studies of mechanism revealed that E Platinum suppressed activation of mTOR and p70S6K by decreasing phosphorylation of Akt, ERK1/2, JNK and p38 involved in mitogen-activated protein kinase signaling. Platinum AKT serine/threonine kinase 1 Homo sapiens