Guanosine Diphosphate

AKT serine/threonine kinase 1 ; Homo sapiens







38 Article(s)
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Pub. Year
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1 34213070 GDP Induces PANC-1 Human Pancreatic Cancer Cell Death Preferentially under Nutrient Starvation by Inhibiting PI3K/Akt/mTOR/Autophagy Signaling Pathway. 2021 Sep 2
2 29242061 Phosphorylation of Ser-525 in βPix impairs Nox1-activating ability in Caco-2 cells. 2018 Jan 15 3
3 29743547 The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles. 2018 May 9 1
4 24598074 Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task. 2014 1
5 25056956 Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production. 2014 Sep 5 2
6 22520755 Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2. 2012 Apr 20 1
7 23050005 Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration. 2012 1
8 21787760 Understanding SOS (Son of Sevenless). 2011 Nov 1 1
9 18480413 Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane. 2008 Jul 2
10 18505730 Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP. 2008 Aug 8 1
11 16597700 In vivo dynamics of Rac-membrane interactions. 2006 Jun 2
12 16702219 Liposomes comprising anionic but not neutral phospholipids cause dissociation of Rac(1 or 2) x RhoGDI complexes and support amphiphile-independent NADPH oxidase activation by such complexes. 2006 Jul 14 1
13 16998826 Rho GTPase activity zones and transient contractile arrays. 2006 Oct 1
14 15649357 The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade. 2005 Jan 11 2
15 15850775 Novel intermediate of Rac GTPase activation by guanine nucleotide exchange factor. 2005 Jun 3 4
16 16049005 ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. 2005 Oct 14 1
17 16101281 Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK). 2005 Aug 23 1
18 16190977 RhoGDIs revisited: novel roles in Rho regulation. 2005 Nov 1
19 12471028 Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam. 2003 Feb 14 3
20 12475976 The guanine nucleotide exchange factor trio activates the phagocyte NADPH oxidase in the absence of GDP to GTP exchange on Rac. "The emperor's nw clothes". 2003 Feb 14 1
21 11779690 Regulation of Vav proteins by intramolecular events. 2002 Jan 1 1
22 11950933 Vav regulates activation of Rac but not Cdc42 during FcgammaR-mediated phagocytosis. 2002 Apr 3
23 12134164 Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism. 2002 Aug 1
24 12432077 Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. 2002 Dec 15 1
25 11513579 Mechanism of NADPH oxidase activation by the Rac/Rho-GDI complex. 2001 Aug 28 1
26 11607839 Vav proteins, adaptors and cell signaling. 2001 Oct 1 1
27 10975833 Rac is involved in early TCR signaling. 2000 Sep 15 1
28 10360579 Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK. 1999 May 27 1
29 9381982 Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases. 1997 1
30 7947751 Ras effector-homologue region on Rac regulates protein associations in the neutrophil respiratory burst oxidase complex. 1994 Nov 15 1
31 8089125 Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac. 1994 Sep 23 1
32 8253741 Biologically active lipids are regulators of Rac.GDI complexation. 1993 Dec 15 1
33 8282094 Regulation of phagocyte function by low molecular weight GTP-binding proteins. 1993 Nov 1
34 8305740 Regulation of NADPH oxidase activity by Rac GTPase activating protein(s). 1993 Nov 1
35 8352776 The nucleotide exchange rates of rho and rac small GTP-binding proteins are enhanced to different extents by their regulatory protein Smg GDS. 1993 Aug 16 1
36 8419353 GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. 1993 Jan 15 2
37 8491184 A novel role for RhoGDI as an inhibitor of GAP proteins. 1993 May 1
38 1938104 A synthetic peptide corresponding to a sequence in the GTPase activating protein inhibits p21ras stimulation and promotes guanine nucleotide exchange. 1991 Jul 1