Title : GDP Induces PANC-1 Human Pancreatic Cancer Cell Death Preferentially under Nutrient Starvation by Inhibiting PI3K/Akt/mTOR/Autophagy Signaling Pathway.

Pub. Date : 2021 Sep

PMID : 34213070






2 Functional Relationships(s)
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1 GDP induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway. Guanosine Diphosphate AKT serine/threonine kinase 1 Homo sapiens
2 Mechanistically, GDP inhibited PI3K/Akt/mTOR/autophagy survival signaling pathway, leading to selective PANC-1 cancer cell death under the nutrition starvation condition. Guanosine Diphosphate AKT serine/threonine kinase 1 Homo sapiens