Title : Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

Pub. Date : 2002 Dec 15

PMID : 12432077






1 Functional Relationships(s)
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1 Importantly, we have identified several novel homologues of DOCK180 that possess this domain and found that many of them directly bind to and exchange GDP for GTP both in vitro and in vivo on either Rac or another Rho-family member, Cdc42. Guanosine Diphosphate AKT serine/threonine kinase 1 Homo sapiens