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AKT serine/threonine kinase 1 ; Homo sapiens







137 Article(s)
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101 29227594 Transcriptional regulation of NOX genes express ion in human breast adenocarcinoma MCF-7 cells is modulated by adaptor protein Ruk/CIN 85. 2016 Jan-Feb 1
102 25942647 Crossroads of PI3K and Rac pathways. 2015 1
103 26107995 Functionalized Multiwalled Carbon Nanotubes as Carriers of Ruthenium Complexes to Antagonize Cancer Multidrug Resistance and Radioresistance. 2015 Jul 15 1
104 26450902 Non-thermal plasma induces AKT degradation through turn-on the MUL1 E3 ligase in head and neck cancer. 2015 Oct 20 1
105 26465677 A Novel Platinum-Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway. 2015 Dec 7 1
106 26514923 Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells. 2015 Dec 2 1
107 26632198 EZH2 phosphorylation regulates Tat-induced HIV-1 transactivation via ROS/Akt signaling pathway. 2015 Dec 21 3
108 26634216 fMLP-Induced IL-8 Release Is Dependent on NADPH Oxidase in Human Neutrophils. 2015 1
109 24068521 Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. 2014 May 1
110 24594691 Human phosphatidylethanolamine-binding protein 4 promoted the radioresistance of human rectal cancer by activating Akt in an ROS-dependent way. 2014 2
111 24792722 Nox1 activation by βPix and the role of Ser-340 phosphorylation. 2014 May 29 1
112 24992302 Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells. 2014 1
113 25072752 Poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells. 2014 Nov 1
114 25135223 Strategy to enhance the anticancer efficacy of X-ray radiotherapy in melanoma cells by platinum complexes, the role of ROS-mediated signaling pathways. 2014 Nov 1 1
115 25305377 Abrus precatorius agglutinin-derived peptides induce ROS-dependent mitochondrial apoptosis through JNK and Akt/P38/P53 pathways in HeLa cells. 2014 Oct 5 2
116 23063593 Herbacetin induces apoptosis in HepG2 cells: Involvements of ROS and PI3K/Akt pathway. 2013 Jan 1
117 23252827 The miR-183/96/182 cluster regulates oxidative apoptosis and sensitizes cells to chemotherapy in gliomas. 2013 Feb 1
118 23353183 Crosstalk from survival to necrotic death coexists in DU-145 cells by curcumin treatment. 2013 May 1
119 24032351 2,3-cis-procyanidins elicit endothelium-dependent relaxation in porcine coronary arteries via activation of the PI3/Akt kinase signaling pathway. 2013 Oct 9 1
120 24113182 Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial-mesenchymal transition of cancer cells. 2013 Oct 10 1
121 22251375 Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes. 2012 Jan 18 1
122 22895800 Involvement of ROS in the inhibitory effect of thermotherapy combined with chemotherapy on A549 human lung adenocarcinoma cell growth through the Akt pathway. 2012 Oct 1
123 23284736 Fo Shou San, an ancient Chinese herbal decoction, protects endothelial function through increasing endothelial nitric oxide synthase activity. 2012 1
124 21123941 XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas. 2011 Jan 2
125 21620957 ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation. 2011 Jul 15 4
126 21837363 Activation of Akt/GSK3β and Akt/Bcl-2 signaling pathways in nickel-transformed BEAS-2B cells. 2011 Nov 1
127 23554696 Activation of Rac1-PI3K/Akt is required for epidermal growth factor-induced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells. 2011 Jul 2
128 19939451 Rac/ROS-related protein kinase C and phosphatidylinositol-3-kinase signaling are involved in a negative regulating cascade in B cell activation by antibody-mediated cross-linking of MHC class II molecules. 2010 Jan 2
129 21132068 Differential sensitization of different prostate cancer cells to apoptosis. 2010 Aug 1
130 19482076 ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells. 2009 Sep 1 8
131 18239155 PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2. 2008 Apr 1
132 18830414 PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability. 2008 Nov 1
133 17318262 Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. 2007 Mar 2
134 17573344 Modulation of intracellular signaling pathways to induce apoptosis in prostate cancer cells. 2007 Aug 17 1
135 16282349 G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth. 2006 Mar 1 4
136 16885344 ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice. 2006 Aug 1 1
137 12614848 Caspase activation is accelerated by the inhibition of arsenite-induced, membrane rafts-dependent Akt activation. 2003 Mar 1 1