Title : Transcriptional regulation of NOX genes express ion in human breast adenocarcinoma MCF-7 cells is modulated by adaptor protein Ruk/CIN 85.

Pub. Date : 2016 Jan-Feb

PMID : 29227594






1 Functional Relationships(s)
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1 Our previousstudies revealed that ROS production by human colorectal adenocarcinoma HT-29 cells is positively correlatedwith adaptor protein Ruk/CIN85 expression while increased levels of Ruk/CIN85 in weakly invasive humanbreast adenocarcinoma MC F-7 cells contribute to their malignant phenotype through the constitutiveactivation of Src/Akt pathway. ros AKT serine/threonine kinase 1 Homo sapiens