Pub. Date : 2011 Nov
PMID : 21837363
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Taken together, these findings demonstrate that activation of Akt, followed by GSK3beta inhibition and Bcl-2, Bcl-XL up-regulation and decrease of ROS generation, along with a synergistic effect of Rb down-regulation may cause apoptosis resistance, contributing to the overall mechanism of nickel carcinogenesis. | ros | AKT serine/threonine kinase 1 | Homo sapiens |